Table 7. The training time of the models with the PDBbind 2016 database.

Dataset	Modela
	Adj-float	Adj-1	Adj-2	Adj-4	Adj-8	Pafnucy
dataset1	541.22 (3.33)	4.84 (0.02)	10.87 (0.06)	27.78 (0.10)	40.30 (0.18)	161.83 (0.04)
dataset2	2238.41 (11.64)	16.41 (0.05)	30.27 (0.02)	70.87 (0.19)	105.94 (0.52)	681.87 (0.12)
dataset3	2952.48 (10.20)	19.22 (0.03)	39.93 (0.16)	69.36 (0.30)	157.68 (0.29)	557.76 (0.13)
dataset4	8065.14 (20.47)	41.52 (0.11)	97.19 (0.27)	192.44 (0.41)	420.81 (1.31)	2236.35 (0.76)

^aComputing time were measured in minute scale.