Table 1.
Administration of the NO‐Donating Lozenge on Vascular Compliance and Reduced Central Pressure After 30 Minutes
| Baseline | After NO Lozenge | P Value | |
|---|---|---|---|
| Mean arterial pressure, mm Hg | 114±3 | 108±3 | .003 |
| Heart rate, beats per min | 77.4±2.4 | 76.2±2.0 | .26 |
| Pulse pressure, mm Hg | 44±3 | 38±2 | .007 |
| Central systolic BP, mm Hg | 127±3 | 122±3 | .01 |
| Central diastolic BP, mm Hg | 95±2 | 94±3 | .25 |
| Central pulse pressure, mm Hg | 31.4±1.9 | 28.7±1.6 | .07 |
| Cardiac output, L/min | 5.4±0.2 | 5.1±0.2 | .07 |
| Total vascular resistance, s*mm Hg/mL | 1.3±0.03 | 1.3±0.03 | .65 |
| Augmentation pressure, mm Hg | 6.2±0.8 | 4.3±0.6 | .02 |
| Augmentation index @75 | 21.2±2.5 | 15.4±1.7 | .01 |
| Pulse wave velocity, m/s | 8.6±0.4 | 8.3±0.4 | .005 |
Abbreviations: BP, blood pressure; NO, nitric oxide. Data are expressed as the average of 20 patients at baseline and a half hour after a single lozenge.