Table 1.
Characteristics of the Patients at Baseline
| Characteristics | Values (n=406) |
|---|---|
| Demographics | |
| Age, y, mean (SD) | 74.8 (9.6) |
| Men, No. (%) | 228 (56.2) |
| Education (range), y | 4.0 (0–30) |
| Clinical characteristics | |
| Diabetes mellitus, No. (%) | 160 (39.4) |
| Hyperlipidimia, No. (%) | 248 (61.1.) |
| Smoking, No. (%) | 167 (41.1) |
| Alcohol, No. (%) | 49 (12.1) |
| AF or CHF | 70 (17.2) |
| Systolic BP, mean (SD) | 153.6 (22.7) |
| Diastolic BP, mean (SD) | 81.9 (12.4) |
| PP, mean (SD) | 71.6 (20.8) |
| Global CDR, 0/0.5/1/2/3a | 169/141/28/24/16 |
| Total MMSE, mean (SD)b | 21.9 (6.8) |
| Admission NIHSS, mean (SD) | 5.24 (5.31) |
| Antihypertensive therapy, No. (%) | 116 (28.6) |
| MRI findings | |
| VBR, mean (SD) | 0.33 (0.05) |
| Lacunes, No. (%) | 317 (78.1) |
| MTLA, 0/1/2/3/4 | 72/136/97/65/36 |
Abbreviations: AF, atrial fibrillation; BP, blood pressure; CDR, clinical dementia rating scale; CHF, congestive heart failure; MMSE, mini‐mental state examination; MTLA, medial temporal lobe atrophy; SD, standard deviation; VBR, ventricular brain ratio. an=378 for global CDR; bn=404 for total MMSE due to unavailable cognitive assessments.