. 2016 Jun 13;18(12):1250–1257. doi: 10.1111/jch.12860

Table 3.

Comparisons of Changes in Laboratory Data

	Control group		^a P Value	Eplerenone group		^a P Value	^b P Value
	0W	12W	^a P Value	0W	12W	^a P Value	^b P Value
Hemoglobin, g/dL	13.7±1.5	13.8±1.7	.43	14.0±1.4	14.0±1.6	1.00	.86
Hematocrit, %	40.9±4.4	40.9±4.5	.90	40.8±4.2	40.9±4.3	.78	.98
Total cholesterol, mg/dL	191±48	192±22	.61	196±29	199±33	.19	1
Triglycerides, mg/dL	197±190	174±92	.32	169±146	157±103	.54	.92
HDL cholesterol, mg/dL	47±11	47±10	.36	56±18	56±17	.86	.75
LDL cholesterol, mg/dL	114±22	111±24	.64	108±26	114±32	.05	.12
AST, U/L	31±21	32±22	.96	27±10	26±11	.95	.87
ALT, U/L	37±37	41±36	.62	30±15	32±21	.48	.71
Uric acid, mg/dL	6.0±1.4	6.1±1.9	.55	6.1±1.4	6.2±1.6	.28	.822
BUN, mg/dL	16.7±4.3	16.6±5.7	.92	16.1±4.9	17.1±4.6	.14	.311
Creatinine, mg/dL	0.91±0.38	0.88±0.36	.35	0.77±0.18	0.80±0.19	.08	.067
Na, mmol/L	141±2	141±2	.36	140±2	140±2	.84	.81
K, mmol/L	4.3±0.4	4.3±0.5	.24	4.2±0.4	4.3±0.4	.12	.059
Fasting blood glucose, mg/dL	147±48	127±36	.01	131±42	127±33	.45	.049
Fasting Insulin, μIU/mL	34.4±66.2	18.6±23.6	.16	19.9±20.1	15.0±12.0	.07	.22
logHOMA‐IR	0.58±0.51	0.51±0.27	.51	0.59±0.49	0.51±0.43	.23	.93
Glycated hemoglobin, %	6.4±1.2	6.2±1.0	.06	6.0±1.1	6.0±1.0	.59	.16
logANP, pg/mL	1.55±0.37	1.60±0.34	.17	1.46±0.31	1.48±0.30	.59	.91
log UACR	1.87±0.83	1.64±0.92	.16	1.43±0.7	1.42±0.74	.91	.15
Urinary Na, mEq/L	120±42	130±49	.72	136±53	144±59	.56	.97
Urinary K, mEq/L	45±18	32±9	<.001	49±21	58±30	.01	<.001

Abbreviations: ALT, alanine aminotransferase; ANP, atrial natriuretic peptide; AST, aspartate aminotransferase; BUN, serum urea nitrogen; HOMA‐IR, homeostatic model assessment of insulin resistance; Na, sodium; K, potassium; UACR, urinary albumin/creatinine ratio.

P value indicates the comparison between week 0 (0W) and week 12 (12W).

P value indicates the comparison of the intergroup difference.