Table 4.
Changes in Measures of Target Organ Damage
| Control Group | P Value | Eplerenone Group | P Value | |||
|---|---|---|---|---|---|---|
| 0W | 12W | 0W | 12W | |||
| Log UACRa | 1.83±0.85 | 1.68±0.93 | .16 | 1.41±0.69 | 1.42±0.74 | .91 |
| FMD, %b | 5.5±1.9 | 5.8±1.9 | .21 | 4.9±1.5 | 5.5±1.7 | .044 |
| Average baPWV, cm/sc | 1590±305 | 1577±209 | .80 | 1529±303 | 1481±336 | .23 |
Abbreviations: 0W, week 0; 12W, week 12; baPWV, brachial‐ankle pulse wave velocity; FMD, flow‐mediated vasodilation; UACR, urinary albumin/creatinine ratio. Data are shown as mean±standard deviation. an=19 for the control group, n=33 for the eplerenone group. bn=19 for the control group, n=31 for the eplerenone group. cn=20 for the control group, n=32 for the eplerenone group.