Table 1.
White Matter Lesions Absent (n=161) | White Matter Lesions Present (n=160) | P Value | |
---|---|---|---|
Age, y | 65.2±14.3 | 76.5±11.1 | <.0001 |
Male | 94 (58.4) | 64 (40.0) | .001 |
Hypertension | 113 (70.2) | 141 (88.1) | .0001 |
Average SBP, mm Hg | 132.1±16.6 | 139.1±17.3 | .0002 |
Average DBP, mm Hg | 76.3±9.3 | 75.4±10.1 | .43 |
Current smoker | 39 (24.2) | 30 (18.8) | .23 |
Ex‐smoker | 36 (22.4) | 32 (20.0) | .60 |
Diabetes | 25 (15.5) | 36 (22.5) | .11 |
Hypercholesterolemia | 17 (10.6) | 15 (9.4) | .72 |
Carotid stenosis ≥50% | 62 (38.5) | 79 (49.4) | .05 |
Hemorrhagic stroke | 6 (3.7) | 14 (8.8) | .06 |
TOAST classification | |||
Large artery | 21 (13.0) | 21 (13.1) | .98 |
Cardioembolism | 53 (32.9) | 43 (26.9) | .24 |
Small artery | 18 (11.2) | 28 (17.4) | .11 |
Other cause | 5 (3.1) | 1 (0.6) | .10 |
Undetermined cause | 58 (36.0) | 53 (33.1) | .58 |
Abbreviations: DBP, diastolic blood pressure; SBP, systolic blood pressure; TOAST, Trial of ORG 10172 in Acute Stroke Treatment. Values are expressed as mean±standard deviation or number (percentage).