Table 3.
Adjusted Results for Clinical Markers of Effectiveness During the Follow‐Up Period
| Chlorthalidone 25 mg Compared With Hydrochlorothiazide 25 mg | Chlorthalidone 25 mg Compared With Hydrochlorothiazide 50 mg | |
|---|---|---|
| Mean incremental mm Hg difference in SBP | −3.16 (−5.25 to −1.07) | −4.6 (−7.4 to −1.8) |
| Mean incremental mm Hg difference in DBP | −2.59 (−3.84 to −1.34) | −3.68 (−5.41 to −1.95) |
| Odds ratio of both SBP and DBP goala attainment | 1.38 (0.98 to 1.94) | 1.81 (1.12 to 2.94) |
Values in parentheses are expressed as 95% confidence interval. Chlorthalidone 25 mg (n=180), hydrochlorothiazide 25 mg (n=355), and hydrochlorothiazide 50 mg (n=177).
a
Systolic blood pressure (SBP) goal is defined as <140 mm Hg, except <130 mm Hg if diabetes is present, and diastolic blood pressure (DBP) goal is defined as <90 mm Hg, except <80 mm Hg if diabetes is present.