Table 1.
Clinical Characteristics in Persistent High CK and Persistent Normal CK (N=250)
| Persistent High CK (n=120) | Persistent Normal CK (n=130) | P Value | |
|---|---|---|---|
| Baseline | |||
| logCK, U/L | 2.55 | 1.94 | |
| Age, y | 61.0 | 61.3 | .8 |
| Men, % | 45.0 | 47.7 | .8 |
| Weight, kg | 81.8 | 77.7 | .009 |
| Height, cm | 170.2 | 169.5 | .4 |
| Body mass index, kg/m2 | 28.1 | 27.0 | .03 |
| Waist‐hip ratio | 0.92 | 0.92 | .3 |
| Systolic blood pressure, mm Hg | 139.8 | 140.0 | .9 |
| Diastolic blood pressure, mm Hg | 80.2 | 78.4 | .1 |
| Hypertension, %a | 68.5 | 60.1 | .1 |
| Use of antihypertensive drugs, % | 40.1 | 30.0 | .08 |
| Follow‐up | |||
| Systolic blood pressure, mm Hg | 140.8 | 138.2 | .2 |
| Diastolic blood pressure, mm Hg | 83.2 | 81.0 | .06 |
| Hypertension, %a | 66.7 | 55.5 | .05 |
| Use of antihypertensive drugs, % | 44.0 | 45.0 | .7 |
| Uncontrolled hypertension, %b | 66.7 | 66.0 | .9 |
| Body mass index, kg/m2 | 28.0 | 27.1 | .06 |
| AUDIT score | 2.8 | 2.7 | .8 |
| Use of statins, % | 23.2 | 23.8 | .9 |
| Diabetes mellitus, % | 1.7 | 3.1 | .5 |
| Strenuous leisure physical activity, %c | 38.6 | 30.9 | .2 |
Abbreviations: AUDIT, alcohol use disorder identification test; CK, creatine kinase. Values are age‐ and sex‐adjusted. Age was adjusted for sex and sex was adjusted for age. aHypertension was defined as a systolic blood pressure value ≥140 mm Hg or diastolic blood pressure value ≥90 mm Hg or use of antihypertensive medication. bOf patients taking antihypertensive drugs. cStrenuous leisure physical activity was defined as activity with the presence of sweating or breathlessness ≥3 hours per week in the past month.