Table 2.
Diagnosis of LVH Based on ECHO vs CMR z Score
| ECHO | CMR z Score (Gold Standard) | |||||
|---|---|---|---|---|---|---|
| LVH– | LVH+ | Total | ||||
| All Patients | Obese | All Patients | Obese | All Patients | Obese | |
| (A) Method g/ht2.7 | ||||||
| LVH– | 3 | 0 | 1 | 1 | 4 | 1 |
| LVH+ | 9 | 7 | 9 | 6 | 18 | 13 |
| Total | 12 | 7 | 10 | 7 | 22 | 14 |
| All patients | Obese patients | |||||
| Sensitivity, 90% (95% CI, 77.5%–100%) | Sensitivity, 85.7% (95% CI, 67.4%–100%) | |||||
| Specificity, 25% (95% CI, 6.9%–43.1%) | Specificity, 0% (95% CI, 0%–0%) | |||||
| PPV, 50% (95% CI, 29.1%–70.9%) | PPV, 46.15% (95% CI, 20.4%–72.3%) | |||||
| NPV, 75% (95% CI, 56.9%–93.1%) | NPV, 0% (95% CI, 0%–0%) | |||||
| AUC, 0.62 (95% CI, 0.35–0.90) | AUC, 0.23 (95% CI, 0–1) | |||||
| (B) Subjective method | ||||||
| LVH– | 5 | 7 | 2 | 5 | 12 | 7 |
| LVH+ | 7 | 3 | 5 | 2 | 10 | 7 |
| Total | 12 | 10 | 7 | 7 | 22 | 14 |
| All patients | Obese patients | |||||
| Sensitivity, 30.0% (CI, 10.8%–49.2%) | Sensitivity, 28.6% (95% CI, 4.9%–52.2%) | |||||
| Specificity, 41.67% (CI, 21.1%–62.3%) | Specificity, 28.6% (95% CI, 4.9%–52.2%) | |||||
| PPV, 30% (CI, 10.8%–49.1%) | PPV, 28.6% (95% CI, 4.9%–52.2%) | |||||
| NPV, 41.67% (CI, 21.1%–62.3%) | NPV, 28.6% (95% CI, 4.9%–52.2%) | |||||
| AUC, 0.36 (CI, 0.15–0.57) | AUC, 0.28 (95% CI, 0.03–0.54) | |||||
Abbreviations: AUC, area under the receiver operating characteristic curve; CMR, cardiovascular magnetic resonance imaging; ECHO, echocardiography; LVH–, left ventricular hypertrophy not present; LVH+, left ventricular hypertrophy present; NPV, negative predictive value; PPV, positive predictive value.