Table 2.
Dosages of Commonly Used Antihypertensive Drugs
| Daily Dosage, mg | ||
|---|---|---|
| Low Dosage | Usual Dosage | |
| Calcium channel blockers | ||
| Nondihydropyridines | ||
| Diltiazem | 120 | 240–360 |
| Verapamil | 120 | 240–480 |
| Dihydropyridines | ||
| Amlodipine | 2.5 | 5–10 |
| Felodipine | 2.5 | 5–10 |
| Isradipine | 2.5 twice daily | 5–10 twice daily |
| Nifedipine | 30 | 30–90 |
| Nitrendipine | 10 | 20 |
| Drugs that target the renin‐angiotensin system | ||
| Angiotensin‐converting enzyme inhibitors | ||
| Benazepril | 5 | 10–40 |
| Captopril | 12.5 twice daily | 50–100 twice daily |
| Enalapril | 5 | 10–40 |
| Fosinopril | 10 | 10–40 |
| Lisinopril | 5 | 10–40 |
| Perindopril | 4 | 4–8 |
| Quinapril | 5 | 10–40 |
| Ramipril | 2.5 | 5–10 |
| Trandolapril | 1–2 | 2–8 |
| Angiotensin receptor blockers | ||
| Azilsartan | 40 | 80 |
| Candesartan | 4 | 8–32 |
| Eprosartan | 400 | 600–800 |
| Irbesartan | 150 | 150–300 |
| Losartan | 50 | 50–100 |
| Olmesartan | 10 | 20–40 |
| Telmisartan | 40 | 40–80 |
| Valsartan | 80 | 80–320 |
| Direct renin inhibitor | ||
| Aliskiren | 75 | 150–300 |
| Diuretics | ||
| Thiazide and thiazide‐like diuretics | ||
| Bendroflumethiazide | 5 | 10 |
| Chlorthalidone | 12.5 | 12.5–25 |
| Hydrochlorothiazide | 12.5 | 12.5–50 |
| Indapamide | 1.25 | 2.5 |
| Loop diuretics | ||
| Bumetanide | 0.5 | 1 |
| Furosemide | 20 twice daily | 40 twice daily |
| Torsemide | 5 | 10 |
| Potassium‐sparing diuretics | ||
| Amiloride | 5 | 5–10 |
| Eplerenone | 25 | 50–100 |
| Spironolactone | 12.5 | 25–50 |
| Triamterene | 100 | 100 |
| β‐Blockers | ||
| Acebutalol | 200 | 200–400 |
| Atenolol | 25 | 100 |
| Bisoprolol | 5 | 5–10 |
| Carvedilol | 3.125 twice daily | 6.25–25 twice daily |
| Labetalol | 100 twice daily | 100–300 twice daily |
| Metoprolol succinate | 25 | 50–100 |
| Metoprolol tartrate | 25 twice daily | 50–100 twice daily |
| Nadolol | 20 | 40–80 |
| Nebivolol | 2.5 | 5–10 |
| Propranolol | 40 twice daily | 40–160 twice daily |
| α‐Adrenergic receptor blockers | ||
| Doxazosin | 1 | 1–2 |
| Prazosin | 1 twice daily | 1–5 twice daily |
| Terazosin | 1 | 1–2 |
| Vasodilators, central α‐agonists, and adrenergic depleters | ||
| Vasodilators | ||
| Hydralazine | 10 twice daily | 25–100 twice daily |
| Minoxidil | 2.5 | 5–10 |
| Central alpha‐agonists | ||
| Clonidine | 0.1 twice daily | 0.1–0.2 twice daily |
| Clonidine patch | TTS‐1, once weekly | TTS‐1, 2, or 3, once weekly |
| Methyldopa | 125 twice daily | 250–500 twice daily |
| Adrenergic depleters | ||
| Reserpine | 0.1 | 0.1–0.25 |
All doses are given once‐daily unless otherwise specified.