Table 4.
Estimated Decline in ASCVD Events in Adults Without Hypertension Eligible For But Not Currently Taking Statin Therapy
| Nonhypertensive, No Statin Group | No. | Statin Intensity | ∅Statin ASCVD10, % | ∅Statin ASCVD10 | ASCVD10 ⊕Statin, No. | Change ASCVD10 Events | Relative ASCVD Reduction, % | Absolute ASCVD Reduction, % | Number Needed to Treat |
|---|---|---|---|---|---|---|---|---|---|
| ASCVD | 2666 | High | 34.5 | 920 | 653 | 267 | 28.9 | 10 | 10 |
| LDL ≥190 mg/dL | 1379 | High | 7.8 | 108 | 55 | 52 | 48.7 | 3.8 | 26 |
| ⊕DM ASCVD10 ≥7.5% | 1379 | High | 19.5 | 269 | 188 | 81 | 30.1 | 5.9 | 17 |
| ⊕DM ASCVD10 <7.5% | 1344 | Moderate | 3.6 | 48 | 39 | 9 | 18.8 | 0.7 | 143 |
| ∅DM ASCVD10 ≥7.5% | 11,241 | High | 15.3 | 1720 | 1169 | 551 | 32.0 | 4.9 | 20 |
| ∅DM ASCVD10 5%–7.4% | 6400 | Moderate | 6.1 | 390 | 307 | 83 | 20.8 | 1.3 | 77 |
| Total (All) | 24,409 | Moderate to high | 14.1 | 3442 | 2416 | 1025 | 29.8 | 4.2 | 24 |
| All minus ⊕DM <7.5%, ∅DM 5%–7.4% | 16,665 | High | 18.1 | 3016 | 2066 | 950 | 32.8 | 5.7 | 18 |
Abbreviations: ASCVD, atherosclerotic cardiovascular disease; ASCVD10, 10‐year risk of atherosclerotic cardiovascular disease; ⊕DM, diabetes mellitus; ∅DM, no diabetes mellitus; LDL, low‐density lipoprotein.