Table 1.
Characteristics of Participants
| Characteristic | (N=220) |
|---|---|
| Demographics | |
| Age, y | 80.7 (4.1) |
| Women | 125 (56.8) |
| Lower education (≤6 y) | 64 (29.1) |
| Clinical characteristics | |
| Current smoking | 17 (7.7) |
| Alcohol ≥14 units per wk | 24 (10.9) |
| History of CVDa | 20 (9.1) |
| Presence of chronic diseasesb | 135 (61.4) |
| MMSE (points) | 26 (25–27) |
| Duration of antihypertensive treatment, y | |
| <1 | 5 (2.3) |
| 1–5 | 57 (25.9) |
| >5 | 149 (67.7) |
| Blood pressure, mm Hg | |
| Systolic | 146 (21) |
| Diastolic | 81 (11) |
| Mean arterial pressure | 102 (13) |
| Pulse pressure | 65 (15) |
| MRI characteristics | |
| WMH volume, mL | 22 (9–56) |
| Periventricular WMH | 132 (60.0) |
| Subcortical WMH | 113 (51.4) |
| Lacunar infarcts | 59 (26.8) |
| Microbleeds | 55 (25.0) |
Abbreviations: MMSE, Mini‐Mental State Examination; MRI, magnetic resonance imaging; WMH, white matter hyperintensity. Data are presented as mean (standard deviation), median (interquartile range), or number (percentage) when appropriate. aCardiovascular disease (CVD) includes myocardial infarction, percutaneous coronary intervention, or coronary artery bypass graft. bChronic diseases include diabetes mellitus, Parkinson's disease, chronic obstructive pulmonary disease, malignancy, and osteoarthritis.