Table 3.
Results of Subgroup Analysis of 24‐h Ambulatory Blood Pressure Change
| Pooled Effects | Trials, No. | Mode | Difference in Means | Standard Error | (Lower limit, Upper Limit) | P Value |
|---|---|---|---|---|---|---|
| Diurnal SBP change | 5 | Random | −3.58 | 2.28 | (−8.04, 0.89) | .117 |
| Diurnal DBP change | 5 | Random | −2.85 | 1.39 | (−5.58, −0.12) | .041 |
| Nocturnal SBP change | 5 | Fixed | −2.74 | 0.77 | (−4.26, −1.23) | <.001 |
| Nocturnal DBP change | 5 | Fixed | −1.75 | 0.53 | (−2.79, −0.71) | .001 |
| 24‐h SBP baseline drugs=0 | 1 | Fixed | −2.10 | 0.84 | (−3.74, −0.46) | .012 |
| 24‐h SBP baseline drugs>0 | 6 | Fixed | −2.73 | 1.14 | (−9.83, 3.83) | .016 |
| 24‐h SBP hypertension | 3 | Fixed | −1.81 | 0.78 | (−3.34, −0.29) | .020 |
| 24‐h SBP resistant hypertension | 4 | Fixed | −3.88 | 1.36 | (−6.55, −1.22) | .004 |
| 24‐h DBP baseline drugs=0 | 1 | Fixed | −1.30 | 0.54 | (−2.35, −0.25) | .015 |
| 24‐h DBP baseline drugs>0 | 6 | Fixed | −3.19 | 0.72 | (−4.59, −1.79) | <.001 |
| 24‐h DBP hypertension | 3 | Fixed | −1.28 | 0.51 | (−2.28, −0.27) | .013 |
| 24‐h DBP resistant hypertension | 4 | Fixed | −3.65 | 0.79 | (−5.19, −2.10) | <.001 |
Abbreviations: DBP, diastolic blood pressure; SBP, systolic blood pressure.