Table 4.
Results of Meta‐Regression of the 24‐h Ambulatory and Diurnal BP Change
| Explanatory Variable | Trials, No. | Patients, No. | 24‐h Ambulatory SBP (P Value) | 24‐h Ambulatory DBP (P Value) | Diurnal SBP (P Value) | Diurnal DBP (P Value) |
|---|---|---|---|---|---|---|
| Effective CPAP pressure, cm/H2O | 7 | 794 | .730 | .214 | <.001 | <.001 |
| CPAP compliance, Hours per night | 7 | 794 | .328 | .016 | <.001 | <.001 |
| Mean age, y | 7 | 794 | .328 | .024 | .004 | .003 |
| Male (decimal) | 7 | 794 | .681 | .324 | .460 | .792 |
| Baseline BMI, kg/m2 | 7 | 794 | .673 | .707 | .082 | .547 |
| Baseline AHI, No. | 7 | 794 | .941 | .649 | <.001 | <.001 |
| Baseline ESS, No. | 7 | 794 | .840 | .122 | .621 | .880 |
| Study duration, mo | 7 | 794 | .097 | .206 | <.001 | <.001 |
| Antihypertensive drugs, No. | 5 | 701 | .405 | .053 | <.001 | <.001 |
| Baseline SBP, mm Hg | 7 | 794 | .201 | .036 | <.001 | <.001 |
| Crossover vs parallel trial | 7 | 794 | .368 | .842 | NA | NA |
Abbreviations: AHI, apnea hypopnea index; BMI, body mass index; BP, blood pressure; CPAP, continuous positive airway pressure; DBP, diastolic blood pressure; ESS, Epworth Sleepiness Scale; NA, not available; SBP, systolic blood pressure.