Table 1.
Antihypertensive Medication Class Use and Renal Function in 10,151 Hypertensive Type 2 Diabetic Patients
| Class | eGFR <30 | eGFR 30–60 | eGFR 60–90 | eGFR >90 | P Value |
|---|---|---|---|---|---|
| No. | 565 | 2230 | 3924 | 3432 | |
| Diuretic | 405 (71.7%) | 1400 (62.8) | 1641 (41.8%) | 892 (26.0%) | <.001 |
| Calcium channel blocker | 281 (49.7) | 818 (36.7) | 949 (24.2) | (548) (16.0) | <.001 |
| β‐Blocker | 413 (73.1) | 1339 (60.0) | 1546 (39.4) | 842 (24.5) | <.001 |
| Angiotensin‐converting enzyme inhibitor | 212 (37.5) | 1236 (50.4) | 2565 (65.4) | 2308 (67.2) | <.001 |
| Angiotensin receptor blocker | 123 (21.8) | 587 (26.3) | 751 (19.1) | 490 (14.3) | <.001 |
| Vasodilator | 73 (12.9) | 58 (2.6) | 26 (0.7) | 11 (0.3) | <.001 |
| Centrally active | 46 (8.1) | 67 (3.0) | 46 (0.2) | 38 (0.1) | <.001 |
| α‐Blockers | 89 (15.8) | 254 (11.4) | 306 (7.8) | 131 (3.8) | <.001 |
| Nitrates | 84 (14.9) | 192 (8.6) | 127 (3.2) | 32 (0.9) | <.001 |
| Direct renin inhibitor | 8 (1.4) | 3 (0.1) | 7 (0.2) | 3 (0.1) | <.001 |
Abbreviation: eGFR, estimated glomerular filtration rate.