Table 1.
Patient Characteristics for the Entire Cohort
| Overall Cohort (N=60) | No Diuretics (n=29) | Diuretics (n=31) | P Value | |
|---|---|---|---|---|
| Age, y | 62.1 (13.2) | 57.2 (12.1) | 66.7 (12.6) | .004 |
| Male sex, % | 63.3 | 66.5 | 61.3 | (χ2) .734 |
| Diabetes mellitus, % | 30 | 27.6 | 32.3 | (χ2) .693 |
| Urine volume per d, mL | 1378 (676) | 1301.7 (436) | 1450 (842) | .4 |
| Antihypertensive medications, No. | 2.3 (1.3) | 1.3 (1) | 3.2 (0.9) | <.0001 |
| Systolic blood pressure, mm Hg | 136.7 (19) | 135.6 (15.7) | 137.7 (21.7) | .663 |
| Diastolic blood pressure, mm Hg | 79 (13.9) | 81.5 (12.8) | 76.7 (14.7) | .181 |
| Body weight, kg | 84.7 (19.8) | 90.5 (19.6) | 79.2 (18.6) | .26 |
| Body mass index, kg/m2 | 30.2 (6.2) | 28.9 (6.7) | 31.4 (5.3) | .117 |
| OH, L | 1 (2.2) | 0.7 (1.4) | 1.35 (2.7) | .26 |
| OH % of ECV | 4.5 (9.3) | 2.9 (6.4) | 5.9 (11.3) | .217 |
| Fat mass, kg | 30.9 (12.6) | 30 (15.1) | 31.7 (10.7) | .598 |
| Fat mass, % of body weight | 35.9 (9.8) | 35.4 (11.1) | 36.3 (8.6) | .703 |
| ECV, L | 19.1 (4.8) | 18.5 (4.8) | 19.7 (4.8) | .352 |
| ICV, L | 21 (5.8) | 21.3 (5.4) | 20.8 (6.1) | .748 |
| ICV:ECV ratio | 1.1 (0.2) | 1.15 (0.13) | 1.06 (0.16) | .017 |
| Creatinine clearance, Cockroft‐Gault; mL/min | 82.3 (32.5) | 89.9 (39.4) | 75.6 (23.7) | .096 |
| Potassium, mEq/L | 4.3 (0.4) | 4.3 (0.4) | 4.4 (0.4) | .352 |
| Sodium, mEq/L | 139.7 (3) | 139.7 (3.4) | 139.7 (2.7) | .967 |
Abbreviations: ECV, extracellular fluid volume; ICV, intracellular fluid volume; OH%, overhydration relative to the extracellular fluid volume; OH, overhydration as measured by bioimpedance. Values are expressed as means (±standard deviations). P values by Student t test between the “no diuretics” and the “diuretics” groups.