Table 2.
Laboratory Data in Relation to Tertiles of PP and Treatment
| Low Tertile (Mean PP=50.3 mm Hg) (<58 mm Hg) | Medium Tertile (Mean PP=63.9 mm Hg) (58–70.7 mm Hg) | High Tertile (Mean PP=82.2 mm Hg) (≥70.7 mm Hg) | ||||
|---|---|---|---|---|---|---|
| B+A (n=1888) | B+H (n=1881) | B+A (n=1924) | B+H (n=1887) | B+A (n=1929) | B+H (n=1990) | |
| Serum glucose, mg/dL | 125.3 (48.2) | 123.9 (44.0) | 128.2 (45.0) | 126.7 (44.4) | 130.0 (48.8) | 130.1 (48.6) |
| Total cholesterol, mg/dL | 182.9 (41.2) | 180.3 (37.4) | 184.4 (39.7) | 183.9 (39.2) | 187.5 (40.5) | 187.9 (40.8) |
| HDL cholesterol, mg/dL | 48.9 (14.0) | 48.1 (13.3) | 49.5 (13.8) | 49.4 (14.2) | 50.4 (14.5) | 51.0 (14.6) |
| hsCRP, mg/L | 0.459 (1.0) | 0.447 (0.7) | 0.466 (1.0) | 0.452 (0.8) | 0.450 (0.9) | 0.457 (0.8) |
| eGFR, mL/min/1.73 m2 | 79.5 (20.8) | 81.1 (21.6) | 79.7 (21.5) | 79.1 (21.3) | 77.5 (21.1) | 77.2 (21.5) |
| GFR (MDRD), % | ||||||
| <60 | 314 (16.6) | 292 (15.5) | 350 (18.2) | 338 (17.9) | 381 (19.8) | 398 (20.0) |
| 60–90 | 1046 (55.4) | 1009 (53.6) | 1031 (53.6) | 1042 (55.2) | 1074 (55.7) | 1136 (57.1) |
| >90 | 524 (27.8) | 576 (30.6) | 538 (28.0) | 503 (26.7) | 471 (24.4) | 453 (22.8) |
Abbreviations: B+A, benazepril+amlodipine; B+H, benazepril+hydrochlorothiazide; HDL, high‐density lipoprotein; hsCRP, high‐sensitivity C‐reactive protein; GFR (MDRD), estimated glomerular filtration rate calculated according to Modification of Diet in Renal Disease; PP, pulse pressure. Data are expressed as number of patients (percentage) or mean (standard deviation) unless otherwise indicated. Missing data in each subgroup varied from 0 to 4.