Table 3.

24‐Hour BP Measurements of the Study Population (N=69) at Baseline and After 6 Weeks of Treatment and Change From Baseline

	OLM 80 mg	OLM 20 mg	AML 5 mg
At baseline
24‐hour ABPM, mm Hg	(n=31)	(n=26)	(n=31)
Systolic	138±11	139±11	139±12
Diastolic	84±9	84±10	85±9
Daytime ABPM, mm Hg
Systolic	143±12	144±13	144±13
Diastolic	87±10	88±11	88±10
Nighttime ABPM, mm Hg
Systolic	129±12	129±11	128±13
Diastolic	75±9	76±9	76±9
After 6 weeks of treatment
24‐hour ABPM, mm Hg	(n=31)	(n=26)	(n=31)
Systolic	127±14a	130±14a	134±8a
Diastolic	76±9a	77±9a	81±7a
Daytime ABPM, mm Hg
Systolic	131±14a	135±16a	138±9a
Diastolic	80±9a	81±10a	85±7a
Nighttime ABPM, mm Hg
Systolic	118±15a	119±12a	125±12
Diastolic	68±9a	68±8a	74±9

Change From Baseline	mm Hg	P Value	mm Hg	P Value	mm Hg	P Value
24‐hour ABPM, mm Hg
Systolic	−11.6	<.001	−7.3	<.001	−4.0	.01
Diastolic	−7.8	<.001	−5.3	<.001	−2.5	.01
Daytime ABPM, mm Hg
Systolic	−11.9	<.001	−7.8	<.001	−4.7	.005
Diastolic	−7.8	<.001	−5.6	<.001	−3.1	.006
Nighttime ABPM, mm Hg
Systolic	−11.2	<.001	−6.5	.004	−3.8	.054
Diastolic	−7.8	<.001	−5.4	.002	−1.8	.132

Abbreviations: ABPM, ambulatory blood pressure monitoring; AML, amlodipine; BP, blood pressure; OLM, olmesartan.

^aIndicates significant reduction compared with baseline values. P<.05 is considered statistically significant.