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(A) The graph highlights the amino acid substitutions in the heavy chain CDR3 region of the Abs with respect to the germline gene. Abs ADI-15912 and ADI-15843 share the same CDR3 sequence. (B) Each column shows three fingerprints for each Ab of the family showing how the amino acid substitutions listed in (A), and conformational changes in the models affect the fingerprints.
