TABLE 2.
Association of regional brain volumes with neurocognitive performance measured by the CNT
| Contrast | Cluster | Peak T | MNI Coordinates | Region | Tissue Type | Lobe | ||
|---|---|---|---|---|---|---|---|---|
| x | y | z | ||||||
| Card sorting test | ||||||||
| 1195 | 6.86 | 58 | 2 | −10 | Superior temporal gyrus | White matter | Temporal lobe | |
| 6.11 | 47 | 0 | −12 | Insula | * | Sublobar | ||
| 4.70 | 54 | 14 | −5 | * | * | Fronto-temporal space | ||
| 4.04 | 58 | −7 | −13 | Middle temporal gyrus | White matter | Temporal lobe | ||
| 3.92 | 56 | 4 | −2 | Superior temporal gyrus | Gray matter | Temporal lobe | ||
| Forward digit span test | ||||||||
| 1671 | 7.72 | −13 | 5 | −11 | Lentiform nucleus | Gray matter | Sublobar | |
| 7.61 | −4 | 15 | −13 | Extra-nuclear | White matter | Sublobar | ||
| 4.17 | −24 | 8 | −12 | Lentiform nucleus | Gray matter | Sublobar | ||
| 1199 | 7.44 | 31 | −16 | 13 | Extra-nuclear | White matter | Sublobar | |
| 4.18 | 31 | −28 | 9 | Extra-nuclear | White matter | Sublobar | ||
| 1323 | 6.98 | −39 | 32 | 37 | Middle frontal gyrus | Gray matter | Frontal lobe | |
| 5.12 | −26 | 32 | 44 | Middle frontal gyrus | Gray matter | Frontal lobe | ||
| 4.71 | −44 | 34 | 28 | Middle frontal gyrus | White matter | Frontal lobe | ||
| Verbal learning test; A5 | ||||||||
| 3214 | 7.37 | 35 | −31 | 27 | Extra-nuclear | White matter | Sublobar | |
| 4.51 | 31 | −20 | 35 | Subgyral | White matter | Frontal lobe | ||
| 1092 | 7.33 | −17 | −30 | 36 | Cingulate gyrus | White matter | Limbic lobe | |
| 4.06 | −28 | −21 | 33 | Subgyral | White matter | Frontal lobe | ||
| Verbal learning test; delayed recall | ||||||||
| 5307 | 7.54 | −18 | −33 | 37 | Cingulate gyrus | White matter | Limbic lobe | |
| 7.01 | −7 | −35 | 29 | Cingulate gyrus | White matter | Limbic lobe | ||
| 6.91 | −23 | −48 | 29 | Subgyral | White matter | Parietal lobe | ||
| 5.80 | −23 | −55 | 20 | Subgyral | White matter | Temporal lobe | ||
| 5.63 | 3 | −33 | 27 | * | * | * | ||
| 5.01 | −32 | −54 | 14 | Subgyral | White matter | Temporal lobe | ||
| 1712 | 6.89 | 26 | 14 | 6 | Extra-nuclear | White matter | Sublobar | |
| 5.11 | 34 | 3 | 8 | Extra-nuclear | White matter | Sublobar | ||
| 4.73 | 26 | 2 | −8 | Lentiform nucleus | Gray matter | Sublobar | ||
| 11211 | 6.71 | 20 | 21 | 18 | Extra-nuclear | White matter | Sublobar | |
| 6.57 | 21 | 8 | 21 | Extra-nuclear | White matter | Sublobar | ||
| 6.31 | 19 | −28 | 37 | Cingulate gyrus | White matter | Limbic lobe | ||
| 6.08 | 17 | 33 | −2 | Extra-nuclear | White matter | Sublobar | ||
| 5.76 | 9 | 33 | 2 | Extra-nuclear | White matter | Sublobar | ||
| 5.66 | 30 | −28 | 31 | Subgyral | White matter | Frontal lobe | ||
| 1671 | 4.93 | −17 | 24 | 32 | Cingulate gyrus | White matter | Limbic lobe | |
| 4.66 | −22 | 11 | 29 | Subgyral | White matter | Frontal lobe | ||
| 4.56 | −18 | 30 | 24 | Cingulate gyrus | White matter | Limbic lobe | ||
*No relevant region, tissue type, or lobe corresponds to the MNI coordinates.
MNI indicates Montreal Neurological Institute.