Table 1.

ROC analysis and t-test of ABC transporter family based on GSE40435 dataset

NO.	Gene	Expression (ccRCC)	Expression (normal)	ccRCC/normal		AUC	p	Gene and ccRCC co-occurrence
1	ABCA1	10.860	9.804	1.108	↑	0.961	<0.0001		≥1
2	ABCA2a	7.135	7.199	0.991	↓	0.604	0.0074		0
3	ABCA3	8.022	7.494	1.070	↑	0.901	<0.0001		0
4	ABCA4	6.769	7.160	0.945	↓	0.883	<0.0001		0
5	ABCA5	6.918	7.027	0.984	↓	0.742	<0.0001		0
6	ABCA6	7.015	7.332	0.957	↓	0.845	<0.0001		0
7	ABCA8	7.059	7.683	0.919	↓	0.946	<0.0001		0
8	ABCA9	6.925	7.227	0.958	↓	0.929	<0.0001		0
9	ABCA10	6.776	6.808	0.995	↓	0.646	<0.0001		0
10	ABCA12	6.728	6.582	1.022	↑	0.883	<0.0001		0
11	ABCA13	6.495	6.614	0.982	↓	0.740	<0.0001		≥1
12	ABCB1	7.870	9.453	0.833	↓	0.982	<0.0001		≥1
13	ABCB2(TAP1)	11.140	8.970	1.242	↑	0.999	<0.0001		≥1
14	ABCB3(TAP2)	6.818	6.662	1.023	↑	0.774	<0.0001		≥1
15	ABCB4	7.096	6.814	1.041	↑	0.744	<0.0001		0
16	ABCB6	8.734	8.257	1.058	↑	0.809	<0.0001		0
17	ABCB8	6.884	6.995	0.984	↓	0.739	<0.0001		0
18	ABCB9	7.292	7.395	0.986	↓	0.735	<0.0001		0
19	ABCB10	8.416	8.183	1.028	↑	0.762	<0.0001		≥1
20	ABCC1	6.973	6.823	1.022	↑	0.881	<0.0001		≥1
21	ABCC2	7.694	8.189	0.940	↓	0.738	<0.0001		≥1
22	ABCC3	8.847	8.059	1.098	↑	0.918	<0.0001		0
23	ABCC4	8.715	8.846	0.985	↓	0.596	0.0238		0
24	ABCC5	7.652	7.821	0.978	↓	0.737	<0.0001		0
25	ABCC6	7.063	7.610	0.928	↓	0.911	<0.0001		0
26	ABCC8	6.607	6.688	0.988	↓	0.755	<0.0001		0
27	ABCC9	7.021	6.891	1.019	↑	0.752	<0.0001		0
28	ABCC10	7.145	7.264	0.984	↓	0.687	<0.0001		0
29	ABCC11	6.722	6.707	1.002	↑	0.579	0.0197		0
30	ABCC13	6.727	6.740	0.998	↓	0.593	0.02		0
31	ABCD1	7.406	7.179	1.032	↑	0.756	<0.0001		≥1
32	ABCD3	7.983	8.618	0.926	↓	0.902	<0.0001		0
33	ABCE1	8.864	8.598	1.031	↑	0.842	<0.0001		0
34	ABCF1	9.295	9.626	0.966	↓	0.877	<0.0001		0
35	ABCF2	7.334	7.283	1.007	↑	0.587	0.0026		0
36	ABCF3	7.363	7.502	0.981	↓	0.736	<0.0001		0
37	ABCG1	7.591	7.139	1.063	↑	0.990	<0.0001		0
38	ABCG2	7.234	7.088	1.021	↑	0.557	0.0036		≥1
39	ABCG4	7.032	7.074	0.994	↓	0.602	0.0035		0

^aNovel genes were marked in bold.