Table 4. .
Pearson Correlation Analysis Between Clinical Periodontal Parameters and GCF Biomarkers in Nondiabetic and T2DM Groupsa,b
| Variables |
TNF-α |
IL-6 |
Ghrelin |
Resistin |
AGEs |
RANKL |
| Plaque scores | ||||||
| Nondiabetic group correlation coefficient | –0.2754 | –0.5490 | 0.7513 | 0.7912 | –0.8356 | –0.8210 |
| P-value | .8923 | .1845 | .0604 | .4113 | .5186 | .7012 |
| T2DM group correlation coefficient | 0.8911 | 0.3985 | 0.4733 | 0.9371 | 0.5011 | 0.4242 |
| P-value | .9936 | .0923 | .0951 | .7253 | .4277 | .1598 |
| Bleeding on probing | ||||||
| Nondiabetic group correlation coefficient | 0.8219 | –0.7511 | 0.5732 | 0.8162 | –0.4848 | 0.8819 |
| P-value | .9615 | .4395 | .0701 | .9110 | .0644 | .5284 |
| T2DM group correlation coefficient | –0.7322 | 0.3941 | 0.4353 | 0.1372 | 0.0194 | 0.6936 |
| P-value | .1348 | .0856 | .6672 | .0226 | .0186 | .3487 |
| Probing depth | ||||||
| Nondiabetic group correlation coefficient | 0.7553 | 0.7346 | 0.4986 | 0.4857 | 0.9536 | 0.4534 |
| P-value | .2364 | .9786 | .9774 | .5698 | .4564 | .5675 |
| T2DM group correlation coefficient | 0.9234 | 0.9483 | 0.7563 | 0.3874 | 0.9484 | 0.9487 |
| P-value | .9546 | .1345 | .3745 | .9867 | .7573 | .8374 |
a
AGE indicates advanced glycation end product; GCF, gingival crevicular fluid; IL, interleukin; RANKL, receptor activator of nuclear factor kappa-B ligand; T2DM, type 2 diabetes mellitus; TNF, tumor necrosis factor.
b
Bold letters indicate statistically significant difference between groups at P < .05.