Table 1.
Organ metastatic burden: following drug treatment and tumor relapse, mice were sacrificed and organ metastatic burden was determined ex-vivo using the Xenogen imaging system by counting the number of organs that showed metastasis.
| Drug treatment | Lung | Brain | Bone | Liver | Spleen | Organ metastatic burden | |
|---|---|---|---|---|---|---|---|
| CTR | 4/5 | 0/5 | 5/5 | 0/5 | 1/5 | 10/25 | 40% |
| DTX | 2/5 | 1/5 | 2/5 | 1/5 | 2/5 | 8/25 | 32% |
| Alis | 0/5 | 0/5 | 1/5 | 2/5 | 2/5 | 5/25 | 20% |
| Alis + DTX | 3/5 | 0/5 | 0/5 | 3/5 | 4/5 | 10/25 | 40% |
| Alis + Gals | 5/5 | 1/5 | 4/5 | 1/5 | 2/5 | 13/25 | 52% |
| Alis + Gals + DTX | 3/5 | 0/5 | 0/5 | 0/5 | 0/5 | 3/25 | 12% |