Skip to main content
. 2021 Feb 13;95(4):1335–1347. doi: 10.1007/s00204-021-02988-3

Table 1.

EC50 complex I and II-driven respiration of 2-hydroxyflutamide in platelets from donors of haplogroups H, J, T and U

Complex EC50 complex-driven respiration (µM)
H J T U
I 118 ± 16.2 49.3 ± 5.55 (0.0390) 69.0 ± 9.72 70.8 ± 9.47
II 144 ± 12.1 63.1 ± 3.92 (0.0200) 79.0 ± 8.96 110 ± 8.80

EC50 complex-driven respiration refers to the concentration of 2-hydroxyflutamide required to reduce complex I/II-driven respiration by 50%. Data are presented as mean ± SEM (p value) of n ≥ 6 independent experiments. P value indicates statistical significance compared with other haplogroups and is only shown if < 0.05.