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. 2021 Feb 11;95(4):1397–1411. doi: 10.1007/s00204-021-02997-2

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© The Author(s) 2021

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Fig. 3 — Activation of steatosis-relevant NRs induced by FDO, DIF, PPC and TBC after 24 h incubation in HepG2 cells. Data represent mean fold changes ± SD (N ≥ 3 independent experiments). Statistic was done by one-way ANOVA with Dunnett’s test (*p ≤ 0.05, **p ≤ 0.01 and ***p ≤ 0.001) against medium control, + indicates relative luciferase signals lower as 0.1 or higher than 10