Table 3.
Results of risk factors analysis of treatment failed in TB patients.
Variables | n | Rate of treatment failed (per 1000 TB) | Univariable analysis | Multivariable analysis | ||
---|---|---|---|---|---|---|
OR (95%CI) | P-value | OR (95%CI) | P-value | |||
Gender | ||||||
Males | 2055 | 86.41 | Referent | Referent | ||
Females | 668 | 28.09 | 0.63 (0.57–0.68) | < 0.001 | 0.72 (0.66–0.78) | < 0.001 |
Age | ||||||
0~ | 148 | 6.22 | Referent | Referent | ||
20~ | 643 | 27.04 | 1.68 (1.41–2.01) | < 0.001 | 1.34 (1.12–1.62) | 0.003 |
40~ | 1140 | 47.94 | 3.05 (2.57–3.63) | < 0.001 | 2.17 (1.80–2.61) | < 0.001 |
60~ | 792 | 33.30 | 2.47 (2.07–2.95) | <0.001 | 1.89 (1.56–2.28) | < 0.001 |
Nationality | ||||||
Han | 1789 | 75.23 | Referent | Referent | ||
Miao | 326 | 13.71 | 1.00 (0.89–1.13) | 0.998 | 0.94 (0.83–1.06) | 0.279 |
Buyi | 239 | 10.05 | 1.13 (0.98–1.29) | 0.089 | 1.08 (0.94–1.24) | 0.289 |
Yi | 77 | 3.24 | 1.95 (1.68–2.23) | 0.993 | 0.99 (0.79–1.25) | 0.946 |
Dong | 98 | 4.12 | 1.00 (0.79–1.26) | 0.862 | 0.83 (0.68–1.02) | 0.083 |
Tujia | 122 | 5.13 | 0.98 (0.80–1.21) | 0.384 | 0.97 (0.81–1.17) | 0.758 |
Others | 72 | 3.03 | 0.92 (0.77–1.11) | 0.016 | 0.80 (0.63–1.01) | 0.058 |
Occupation | ||||||
Peasant workers | 2340 | 98.40 | Referent | Referent | ||
Homemakers and unemployed persons | 137 | 5.76 | 1.00 (0.84–1.19) | 0.977 | 1.11 (0.93–1.33) | 0.237 |
Students | 131 | 5.51 | 0.56 (0.47–0.66) | < 0.001 | 0.92 (0.76–1.11) | 0.380 |
Retired persons and cadres and staff | 43 | 1.81 | 0.78 (0.57–1.05) | 0.104 | 0.77 (0.57–1.05) | 0.059 |
Others | 72 | 3.03 | 0.61 (0.48–0.77) | < 0.001 | 0.72 (0.57–0.91) | 0.007 |
Local registered residence | ||||||
Yes | 2489 | 104.67 | Referent | Referent | ||
No | 234 | 9.84 | 0.84 (0.74–0.97) | 0.013 | 0.97 (0.84–1.11) | 0.652 |
Source of patients | ||||||
Clinical consultation | 1323 | 55.63 | Referent | Referent | ||
Referral | 836 | 35.15 | 0.92 (0.84–1.00) | 0.051 | 0.87 (0.80–0.95) | 0.002 |
Following up | 384 | 16.15 | 0.80 (0.71–0.89) | < 0.001 | 0.86 (0.76–0.97) | 0.011 |
Recommended for symptoms | 96 | 4.04 | 1.84 (1.49–2.27) | < 0.001 | 1.49 (1.20–1.84) | < 0.001 |
Physical examinations | 33 | 1.39 | 0.50 (0.35–0.71) | < 0.001 | 0.98 (0.69–1.39) | 0.897 |
Others | 51 | 2.14 | 1.48 (1.12–1.96) | 0.006 | 1.29 (0.97–1.71) | 0.086 |
Clinical classification | ||||||
Type I | 0 | 0.00 | Referent | |||
Type II | 25 | 1.05 | 10,145,695.39 (0.00) | 0.996 | ||
Type III | 2673 | 112.40 | 19,244,084.80 (0.00) | 0.996 | ||
Type IV | 25 | 1.05 | 6,785,381.10 (0.00) | 0.996 | ||
Type V | 0 | 0.00 | 1.00 (0.00) | 1.000 | ||
Diagnosis | ||||||
Etiological positivity | 1758 | 73.93 | Referent | Referent | ||
Etiological negative | 950 | 39.95 | 0.26 (0.24–0.28) | < 0.001 | 0.31 (0.29–0.34) | < 0.001 |
Pure tuberculous pleurisy | 11 | 0.46 | 0.11 (0.06–0.20) | < 0.001 | 0.17 (0.09–0.30) | < 0.001 |
Others | 4 | 0.17 | 0.22 (0.08–0.59) | 0.003 | 0.34 (0.13–0.91) | 0.032 |
Severe cases | ||||||
Yes | 782 | 32.88 | Referent | Referent | ||
No | 1941 | 81.62 | 0.40 (0.36–0.43) | < 0.001 | 0.48 (0.44–0.52) | < 0.001 |
Therapeutic category | ||||||
Initial treatment | 2224 | 93.52 | Referent | Referent | ||
Re-treated | 499 | 20.98 | 3.40 (3.08–3.75) | < 0.001 | 1.87 (1.69–2.07) | < 0.001 |