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. 2021 Apr 8;12:2102. doi: 10.1038/s41467-021-22041-2

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© The Author(s) 2021, corrected publication 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — a Representative magnetic resonance imaging of an emmetropic control eye and a highly myopic eye. The capped lines represent the equatorial diameter of lens. The dotted curves represent the anterior surface of lens showing an obviously flatter lens in highly myopic eyes. b Lens equatorial diameter (n = 144 in emmetropic group vs. 105 in highly myopic group, p = 1.39e−45). c Maximum cross-sectional area of lens (n = 144 in emmetropic group vs. 105 in highly myopic group, p = 7.35e−14). d Lens volume (n = 5 in emmetropic group vs. 5 in highly myopic group, p = 2.42e−5). e Lens thickness (n = 144 in emmetropic group vs. 105 in highly myopic group, p = 0.208). Results are expressed as mean ± SD. Level of significance was detected using two-sided Student’s t test (b–e). ****p < 0.0001 and ns represents no significant difference. Source data are provided as a Source Data file.