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Evolutionary conservation of the 21 amino acid regulatory motif in the PMEL N-terminus. Evolutionary conservation of PMEL residues 70–90 in mammals, birds, reptiles, amphibians, and fish. The coloring scheme is
taken from Fig. 4B (essential residues, red; important, but not essential residues, orange; largely dispensable residues, green). Residues that are 100% conserved are labeled with an asterisk.
