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. 2021 Apr 8;11:7792. doi: 10.1038/s41598-021-85906-y

Table 2.

Antithrombotic therapies and vascular events in COVID-19 patients and with SARS-CoV-2 negative pneumonia.

COVID-19 (N = 127) SARS-CoV-2 negative Pneumonia (N = 24) p
Antithrombotic therapy
None, % 22.0% (N = 28) 45.8% (N = 11) 0.015
Prophylactic LMWH, % 65.4% (N = 83) 54.2% (N = 13) 0.296
Intermediate/treatment dose LMWH, % 12.6% (N = 16) 0% 0.076
Thrombotic events, % (95%CI)
Overall 5.5% (2.2–11.0%) (N = 7) 0% (0–14.2%) 0.004*
ICU 15.2% (5.1–35.9%) (N = 5)
Non-ICU 2.1% (0.3% -7.5%) (N = 2)
Bleeding events, % (95%CI)
Overall 3.8% (1.2–8.6%) (N = 5) 0% (0–14.2%) 0.448*
ICU 6.1% (0.7–20.2%) (N = 2)
Non-ICU 3.2% (0.7–9.0%) (N = 3)

Bold values denote statistical significance at the p < 0.05 level.

ICU intensive care unit, LMWH low molecular weight heparin.

*p value of 0.013 for thrombotic events in ICU vs. non-ICU COVID-19 patients, and p value of 0.604 for bleeding events in ICU vs. non-ICU COVID-19 patients.