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. Author manuscript; available in PMC: 2022 Apr 9.
Published before final editing as: Neuromodulation. 2020 Oct 9:10.1111/ner.13287. doi: 10.1111/ner.13287

Table 1.

Demographics and TMS details by BDNF genotyping

Val/Val Val/Met §p-val #Met/Met
N = 45 27
60.0%
16
35.5%
--- 2
4.4%
110% group
*N 7 4 --- ---
 Age (years) 27.7 (±10.1) 26.5 (±9.5) n.s. ---
 Sex (F/M) 5/2 3/1 --- ---
 Caucasian 4 2 --- ---
 Asian 0 1 --- ---
 African-American 3 1 --- ---
 Scalp-to-coil distance (mm) 17.5 (±2.7) 18.4 (±2.7) n.s. ---
 rMT (%) 49.6 (±7.9) 66.7 (±24.5) n.s. ---
 SI (%MSO) 55.4 (±9.7) 71.2 (±22.5) n.s. ---
1 mV group
 N 19 11 --- 2
 Age (years) 23.6 (±5.7) 25.4 (±7.0) n.s 31.5 (±4.9)
 Sex (F/M) 10/9 4/7 --- 0/2
 Caucasian 6 7 --- ---
 Asian 1 3 --- ---
 African-American 8 1 --- ---
 Mix 2 0 --- ---
 Unknown 2 --- --- 2
 Scalp-to-coil distance (mm) 18.2 (±2.2) 17.6 (±3.2) n.s. 15.1 (±2.4)
 rMT (%MSO) 48.7 (±8.3) 41.6 (±8.1) 0.050
r=0.36
43.5 (±14.8)
 SI (%MSO) 56.4 (±9.7) 49.7 (±9.3) 0.073
r=0.33
51.5 (±20.5)
 SI/rMT 116.0 (±7.6) 120.2 (±14.2) n.s. 117.2 (±7.1)
*

two participants in the 110% group were excluded from further analysis because they were deemed outliers; refer to text for more details.

#

Met/Met carriers excluded from the final analysis because of small sample size

§

P-values from Wilcoxon rank sum test

Abbreviations: F = Female, M = Male, rMT = Resting motor threshold, SI = stimulation intensity, MSO = maximum stimulator output, r = estimate of effect size for Wilcoxon rank sum test; mm = millimeters