Table 3.
Comparison of the VAS of gastrointestinal symptoms and stress of participants between the baseline and endpoint.
| Baseline (n = 36) | 8 weeks (n = 36; LOCF) | Mean differences (Endpoint-baseline) | p-value* | ||||
|---|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | Mean differences | SD | ||
| VAS of gastrointestinal symptoms | |||||||
| Total | 24.47 | 16.65 | 16.28 | 11.96 | −8.19 | 12.91 | 0.001 |
| Dry mouth | 4.28 | 2.89 | 3.42 | 2.62 | −0.86 | 2.71 | 0.064 |
| Difficulty swallowing | 1.17 | 1.77 | 1.08 | 2.09 | −0.08 | 1.61 | 0.758 |
| Decreased appetite | 2.50 | 2.58 | 1.33 | 1.79 | −1.17 | 2.85 | 0.019 |
| Nausea or vomiting | 1.08 | 1.65 | 0.75 | 1.34 | −0.33 | 1.37 | 0.154 |
| Flatulence | 3.69 | 2.85 | 2.56 | 2.71 | −1.14 | 2.77 | 0.019 |
| Gastralgia | 2.78 | 3.21 | 1.94 | 2.63 | −0.83 | 2.29 | 0.036 |
| Upper abdominal pain | 1.61 | 2.36 | 0.81 | 1.51 | −0.81 | 1.95 | 0.018 |
| Lower abdominal pain | 1.72 | 2.29 | 0.97 | 1.56 | −0.75 | 2.03 | 0.034 |
| Constipation | 2.86 | 3.07 | 2.06 | 2.37 | −0.86 | 1.79 | 0.010 |
| Diarrhea | 2.78 | 2.96 | 1.36 | 1.69 | −1.42 | 2.57 | 0.002 |
| VAS of stress | 6.44 | 1.61 | 5.22 | 1.74 | −1.22 | 1.84 | <0.001 |
*
Changes between the baseline and endpoint were assessed by a paired t-test.
VAS, Visual Analog Scale.