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. 2021 Mar 26;15:629323. doi: 10.3389/fnins.2021.629323

TABLE 9.

Studies and experimental characteristics of tES literature for TBI.

Authors Subjects Stimulation parameters
Neuroimaging
Conclusion
Type Current Duration Location Type Feature
Zhang et al., 2020 10 tDCS 2 mA, 20 min twice daily, 5 sessions per week for 4 weeks Anode: Prefrontal area and left DLPFC, cathode: neck and F4. EEG Approximate entropy and cross-approximate entropy Relative power in A-tDCS over the prefrontal area and left DLPFC improves psychomotor inhibition state. The recovery might be related to increased excitability in local and distant cortical networks connecting the sensorimotor area to the prefrontal area.
Straudi et al., 2019 10 tDCS 2 mA, 40 min 5 sessions per week for 2 weeks Anode: bilaterally primary motor cortex, cathode: Nasion. EEG delta (1–3.5 Hz), theta (3.5–7.5 Hz), alpha1 (8–10 Hz), alpha2 (11–13 Hz), beta1 (13.5–18 Hz), beta2 (18.5–30 Hz) This study tested and evaluated the preliminary effects of bilateral anodal transcranial direct current stimulation in patients with disorders of consciousness.
O’Neil-Pirozzi et al., 2017 8 tDCS 2 mA, 20 min 3 sessions (48 h apart) Anode: left DLPFC, cathode: right supraorbital area. EEG Individuals with memory impairments
Power spectrum in theta (4–8 Hz), alpha secondary to chronic TBI may benefit from
(8–13 Hz), and P300. LDLPFC anodal tDCS.
Power spectrum in
Ulam et al., 2015 26 tDCS 1 mA, 20 min 10 sessions consecutive day Anode: left DLPFC (F3), cathode: right supraorbital area (Fp2). EEG delta (1–4 Hz), theta (4–8 Hz), alpha (8–10 Hz), beta1 (12–25 Hz), beta2 (25–30 Hz) Ten anodal tDCS sessions may beneficially modulate regulation of cortical excitability for patients with TBI.
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