Table 4.
Treatment decisions in case 1.
Induction of remission (Q14) | |||
1 | Intravenous Methylprednisolone (IVMP) over 5 days, followed by oral prednisolone | 68/73 | 93.2% |
2 | Intravenous Cyclophosphamide every month for 4-6 months | 47/73 | 64.3% |
3 | Mycophenolate mofetil (MMF) | 9/73 | 12.3% |
4 | Oral prednisolone | 3/73 | 4.1% |
Prophylaxis of thromboembolic events (Q15) | |||
1 | IV heparin initially | 46/70 | 65.7% |
2 | Acetyl salicylic acid (ASA) | 19/70 | 27.1% |
3 | Combination of ASA and clopidogrel | 5/70 | 7.1% |
4 | “Others”: including low molecular weight heparin, Heparin 100 IU/kg/12hr | 13/70 | 18.6% |
- | Warfarin, clopidogrel alone or direct oral anticoagulants (DOAC); | 0 | 0 |
Post-acute phase thrombosis prophylaxis (Q16) | |||
1 | ASA | 33/70 | 47.1% |
2 | Subcutaneous heparin | 16/70 | 22.9% |
3 | Combination of ASA and clopidogrel | 10/70 | 14.3% |
4 | Warfarin | 8/70 | 11.4% |
5 | Clopidogrel | 4/70 | 5.7% |
6 | DOACs | 2/70 | 2.9% |
7 | None | 1/70 | 1.4% |
Duration of thrombosis prophylaxis (Q17) | |||
3 months | 7/70 | 10% | |
6 months | 9/70 | 12.9% | |
12 months | 13/70 | 18.6% | |
18 months | 3/70 | 4.3% | |
24 months | 13/70 | 18.6% | |
36 months | 9/70 | 12.9% | |
None | 1/70 | 1.4% | |
Immune modulating maintenance treatment (Q18) | |||
1 | MMF | 53/73 | 72.6% |
2 | Azathioprine | 15/73 | 20.5% |
3 | Oral prednisolone | 13/73 | 17.8% |
4 | Oral cyclophosphamide (following Fauci scheme) | 1/73 | 1.4% |
4 | TNF inhibitors | 1/73 | 1.4% |
Duration of immune modulating treatment (Q19) | |||
3 months | 3/73 | 4.1% | |
6 months | 4/73 | 5.5% | |
12 months | 12/73 | 16.4% | |
18 months | 14/73 | 19.2% | |
24 months | 27/73 | 37.0% | |
36 months | 4/73 | 5.5% | |
Duration of oral corticosteroid treatment, including slow taper (Q20) | |||
3 months | 15/72 | 20.8% | |
6 months | 30/72 | 41.7% | |
12 months | 11/72 | 15.3% | |
18 months | 3/72 | 4.2% | |
24 months | 4/72 | 5.6% | |
36 months | 1/72 | 1.4% | |
None | 1/72 | 1.4% |