Table 1.
Patient characteristics and cerebrospinal fluid (CSF) parameters for the different patient groups.
| Patient characteristics | CSF parameters | ||||||
|---|---|---|---|---|---|---|---|
| Diagnosis | n | Age |
Sex (f/m) |
Cells/μl |
Protein (mg/dl) |
Glucose (mg/dl) |
AI CSF/ serum (× 10−3) |
| Newly diagnosed PCNSL | 32 | 52 (21–85) | 14/18 | 7 (1–408) | 66 (9–604) | 64 (41–93) | 10 (4–96) |
| Newly diagnosed SCNSL | 8 | 67 (53–90) | 3/5 | 7 (2–369) | 89 (50–221) | 53 (34–103) | 13 (8–53) |
| Relapsed PCNSL | 14 | 64 (23–81) | 6/8 | 8 (1–202) | 88 (39–448) | 63 (25–99) | 18 (3–65) |
| PCNSL complete remission | 22 | 70 (31–80) | 9/13 | 1 (0–8) | 54 (30–204) | 65 (46–112) | 9 (4–49) |
| Primary brain tumor (PBT) | 24 | 60 (21–83) | 8/16 | 2 (0–204) | 57 (25–193) | 60 (48–89) | 8 (3–50) |
| Secondary brain tumor (SBT) | 23 | 63 (31–83) | 11/12 | 5 (0–165) | 65 (26–336) | 63 (10–98) | 7 (4–55) |
| Autoimmune inflammatory disease (AID) | 29 | 48 (19–76) | 19/10 | 9 (0–144) | 54 (23–128) | 60 (25–76) | 7 (3–17) |
| Neuroinfectious disease (NID) | 7 | 58 (20–76) | 1/6 | 16 (1–596) | 64 (49–104) | 54 (36–65) | 12 (7–13) |
| Other neurologic disease (OND) | 18 | 57 (30–84) | 12/6 | 2 (0–7) | 45 (20–130) | 65 (55–116) | 6 (2–21) |
| Historical non-lesional controls | 101 | 53 (18–87) | 48/53 | 1 (0–13) | 44 (22–292) | 62 (45–104) | 6 (2–16) |
For age, cells, protein and glucose levels and antibody index, median with range was calculated. n, number of patients of each group; f, females; m, males; AI, albumin index.