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. 2021 Mar 26;12:647976. doi: 10.3389/fphys.2021.647976

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Copyright © 2021 Pedreros-Lobos, Calderón-Jofré, Moraga and Moraga.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Plasma concentration of hsCRP in miners exposed to CIHH at several altitudes. The horizontal thick line represents a mean value of hsCRP at each altitude. The horizontal dotted line represents a cut-off of cardiovascular risk (<1 mg/L, low; >1 and <3, moderate; and >3 high). Asterisks represent a significant difference between sea level and 2,500 m (p < 0.05) and double asterisks represent a significant difference between 1,600 and 2,500 m (p < 0.05).