Table 3.

Cox regression model associations between clinicopathologic characteristics and mortality in stage IV CRC patients.

Variables	Univariate analysis		Multivariate analysis
	HR (95% CIs)	p	HR (95% CIs)	p
PIK3CA exon 20 mutation (vs. wild-type)	2.52 (1.38-4.59)	0.003	2.19 (1.19-4.03)	0.012
Right colon (vs. others)	2.22 (1.37-3.60)	0.001	2.40 (1.47-3.94)	0.001
Poor differentiation (vs. others)	2.47 (1.49-4.11)	<0.001	2.39 (1.42-4.02)	0.001
Age > 75 years (vs. others)	2.13 (1.22-3.73)	0.008	2.15 (1.21-3.80)	0.009

CIs, confidence intervals; HR, hazard ratio.