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. 2021 Mar 26;11:654684. doi: 10.3389/fonc.2021.654684

Table 2.

CD276 related clinical trials.

Condition or disease Status
Relapsed and refractory neuroblastoma (NB) Recruiting
CD276 positive solid tumor Recruiting
Advanced CD276 positive solid tumor Recruiting
Relapsed / refractory Acute Myeloid Leukemia Recruiting
Central nervous system locoregional adoptive therapy Recruiting
Recurrent Glioblastoma / Refractory Glioblastoma Recruiting
Recurrent Glioblastoma / Refractory Glioblastoma Recruiting
Neuroblastoma, Rhabdomyosarcoma, Osteosarcoma, Ewing Sarcoma, Wilms Tumor, Desmoplastic Small Round Cell Tumor Completed
Advanced Solid Tumor, Metastatic Castrate Resistant Prostate Cancer, Non-small Cell Lung Cancer, Triple Negative Breast Cancer Recruiting
Melanoma, Head and Neck Cancer, Non-small Cell Lung Cancer, Urethelial Carcinoma Active, not recruiting
Advanced Solid Tumors Active, not recruiting
Melanoma, Non-small Cell Lung Cancer Completed
Melanoma Terminated
Prostate Cancer Active, not recruiting
Prostate Cancer, Melanoma, Renal Cell Carcinoma, Triple-negative Breast Cancer, Head and Neck Cancer, Bladder Cancer, Non-small Cell Lung Cancer Completed

MGD009: B7-H3 x CD3 DART protein, is also known as orlotamab.

MGC018: Anti-B7-H3 antibody drug conjugate.

MGA012: Anti-PD-1 antibody, is also known as INCMGA00012.

MGA271: is also known as enoblituzumab.