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. 2021 Mar 26;8:650881. doi: 10.3389/fmolb.2021.650881

FIGURE 4.

FIGURE 4

ARPPs obtain both compact and extended conformations. (A,B) The representation of different conformers of ARPP-16 and ARPP-19 calculated by ENSEMBLE program using chemical shifts (Cα, Cβ, and H), R2 relaxation rates from NMR spectroscopy and the SAXS data. The structure of different conformers obtained from ENSEMBLE calculation shows the conformational freedom of ARPPs. The Dmax of each representative structure is shown. (C) Maximum distance (Dmax) distributions of ARPPs obtained from EOM analyses of the SAXS data plotted as function of frequency (a.u.) reveals that with both ARPPs, the compact conformations are more favored than extended ones.