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. 2021 Mar 26;8:660367. doi: 10.3389/fmed.2021.660367

Table 2.

Summary of finding table.

Outcomes Anticipated absolute effects* (95% CI) Relative effect (95% CI) No. of participants (studies) Certainty of the evidence (GRADE)
Risk with BLS Risk with ALS
Mortality (CTs) 139 per 1,000 156 per 1,000 (133 to 180) OR 1.14 (0.95 to 1.36) 3,928 (2 studies) ⊕ ⊕ ⊕ ○ Moderate
Mortality (OS) 161 per 1,000 231 per 1,000 (201 to 263) OR 1.56 (1.31 to 1.86) 97,062 (8 studies) ⊕ ○○ ○ Very low
Disability of CNS (CTs) 273 per 1,000 296 per 1,000 (248 to 348) OR 1.12 (0.88 to 1.42) 1,394 (2 studies) ⊕ ⊕ ○ ○ LOW
On-scene time (CTs) The mean total time on scene was 0 MD 0.96 lower (6.64 lower to 4.72 higher) - 3,034 (2 studies) ⊕ ⊕ ⊕ ○ Moderate
On-scene time (OS) The mean on-scene time was 0 MD 1.26 higher (0.07 higher to 2.45 higher) - 1,258 (3 studies) ⊕ ⊕ ○ ○ LOW
*

The risk in the ALS group (and its 95% confidence interval) is based on the assumed risk in the BLS group and the relative effect of the ALS (and its 95% CI).

CI, confidence interval; BLS, basic life support; ALS, advanced life support; GRADE, The Grading of Recommendations Assessment, Development and Evaluation, RCT, randomized control trial; OS, observational study; OR, odds ratio; CNS, central nerve system; MD, mean difference.