. 2021 Mar 26;11:590202. doi: 10.3389/fcimb.2021.590202

Table 1.

Statistically different phyla, families, and genera (16S rRNA gene amplicon sequencing) found in fecal samples of infants at 6 months of age (T2).

Taxon	metadata	feature	value	coef	Stderr	N	pval	qval	[factor] IQR (median)	[factor] IQR (median)
									[CS]	[VD]
Phylum	Delivery	Bacteroidetes	VD	0.85	0.36	53	0.021	0.209	0.38–0.87 (0.45)	0.44–37.1 (14.86)
									(FB)	(nFB)
Family	Firstborn	Clostridiales Incertae Sedis XIII	nFB	−0.12	0.03	53	0.001	0.108	0.01–0.01 (0.01)	0.00–0.01 (0.01)
	Firstborn	Clostridiaceae	nFB	−0.50	0.16	53	0.003	0.130	0.31–4.06 (0.81)	0.19–0.55 (0.23)
	Firstborn	Peptostreptococcaceae	nFB	−0.62	0.19	53	0.002	0.130	0.04–0.88 (0.32)	0.02–0.08 (0.04)
	Firstborn	Planctomycetaceae	nFB	0.10	0.03	53	0.003	0.130	ND*	0.00–0.01 (0.00)
									[_EBF]	*[_NeBF]*
	Feeding	Ruminococcaceae	_NeBF	0.63	0.15	53	<0.0001	0.011	0.12–0.22 (0.15)	0.19–2.19 (1.41)
Genus	Delivery	Propionibacterium	VD	−0.22	0.05	53	<0.001	0.031	[CS] 0.00–0.01 (0.00)	[VD] ND*
	Delivery	Thiomicrospira	VD	−0.15	0.04	53	<0.001	0.031	0.00–0.01 (0.01)	ND*
	Delivery	Streptacidiphilus	VD	−0.23	0.07	53	0.002	0.210	0.00–0.02 (0.01)	0.00–0.01 (0.00)
									[_EBF]	*[_NeBF]*
	Feeding	Flavonifractor	_NeBF	0.99	0.25	53	<0.001	0.112	0.00–0.01 (0.00)	0.01–1.25 (0.06)
	Feeding	Erysipelotrichaceae Incertae Sedis	_NeBF	0.79	0.25	53	0.003	0.218	0.01–0.01 (0.01)	0.01-1.24 (0.09)
	Feeding	Romboutsia	_NeBF	0.59	0.18	53	0.002	0.218	0.00–0.01 (0.00)	0.00–0.22 (0.02)
	Feeding	Staphylococcus	_NeBF	−0.51	0.17	53	0.003	0.218	0.01–0.15 (0.02)	0.00–0.01 (0.01)
	Feeding	Faecalicoccus	_NeBF	0.21	0.06	53	0.002	0.218	ND*	0.00–0.01 (0.00)
	Feeding	Sulfurimonas	_NeBF	0.15	0.05	53	0.003	0.218	0.00–0.01 (0.00)	0.01–0.01 (0.01)
	Feeding	Clostridium_IV	_NeBF	0.47	0.16	53	0.005	0.232	0.01–0.04 (0.01)	0.02–0.11 (0.06)
	Feeding	Oribacterium	_NeBF	0.22	0.08	53	0.005	0.232	0.01–0.02 (0.01)	0.02–0.03 (0.02)

VD, vaginal delivery; CS, caesarean section; _EBF, exclusive breastfed; _NeBF, combined or exclusive formula-feeding; FB, first-born; nFB, not first-born; IQR, interquartile range (25^th–75^th percentile). *ND: not detected within all samples belonging to the considered group.