Table 1.
In silico analysis of putative phosphorylation sites of cSrc over PR.
| ID | Position | AA | Kinase | Score | E-value | Peptide | |
|---|---|---|---|---|---|---|---|
| Netphos 3.1 | Progesterone Receptor Homo sapiens AAA60081.1 |
87 | Y | SRC | 0.516 | VEGAYSRAE | |
| EGFR | 0.444 | ||||||
| KinasePhos | 87 | Y | SRC | 13 | VEGAYSRAE | ||
| GPS 5.0 | 87 | Y | TK/SRC/SRCA/YES1 | 27.217 | LSDVEGAYSRAEATR |
Three different databases to predict phosphorylation sites were used to analyze the potential role of cSrc in PR phosphorylation. One putative tyrosine residue in the amino acid 87of PR was found in three databases: NetPhos 3.1, KinasePhos, and GPS 5.0.