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. 2021 Mar 26;12:651851. doi: 10.3389/fphys.2021.651851

Table 2.

Meta-analyzed modifying effects on pre- and post-exercise serum concentration of high-sensitivity cardiac troponin T (hs-cTnT), and the random effects expressed as standard deviations (SD).

Factor effect or SD, ×/÷90%CL Decisionh
Modifying effects on pre-exercise hs-cTnT
    Female/male 0.5, ×/÷3.1 Moderate ↓
    Agea 0.9, ×/÷1.4 Small ↓
Modifying effects on post-exercise hs-cTnT
    Female/male 3.4, ×/÷5.6 Very large ↑
    Agea 0.7, ×/÷1.8 Moderate ↓
    Pre-exercise hs-cTnTb 1.5, ×/÷2.3 Moderate ↑
    Exercise heart ratec 0.9, ×/÷1.5 Trivial
    Exercise durationd 2.4, ×/÷1.7 Large ↑***
Mode comparisons
       Cycling/running 0.9, ×/÷1.3 Small ↓
       Swimming/running 0.9, ×/÷1.7 Trivial
       Triathlon/running 0.8, ×/÷1.9 Small ↓
       Rowing/running 0.1, ×/÷2.4 Extremely large ↓****
Post-exercisee/pre-exercise hs-cTnT
    at 0.7 h 2.9, ×/÷1.3 Large ↑****
    at 1.7 h 4.9, ×/÷1.3 Very large ↑****
    at 2.9 h 7.5, ×/÷1.3 Very large ↑****
    at 5.8 h 6.4, ×/÷1.3 Very large ↑****
    at 12.5 h 3.8, ×/÷1.3 Large ↑****
    at 25 h 2.1, ×/÷1.3 Large ↑****
    at 57 h 1.0, ×/÷1.4 Trivial
Random-effect SDf
    Between bouts (pre-exercise) 1.3, ×/÷ 1.1 Moderate***
    Between bouts (post-exercise) 1.2, ×/÷1.2 Small
    Within bouts (post-exercise) 1.1, ×/÷1.1 Small**
    Between settings (post-exercise)g 1.2, ×/÷1.2 Moderate

90%CL, 90% compatibility limits; ↑, increase; ↓, decrease.

a

Effect of a 25-year difference (~2 between-subject SD).

b

Effect of a 3.2-fold difference (~2 between-subject SD).

c

Effect of a 20-min−1 difference (~2 between-study SD).

d

Effect of a four-fold difference (~2 between-study SD).

e

Times shown are post-exercise time plus half the exercise duration.

f

×/÷90%CL are approximate.

g

Combination of the post-exercise between- and within-bout SD.

h

Observed magnitude with magnitude-based decision.

Clear effects are shown with the probability of a true substantial magnitude

**

(likely,

***

very likely,

****

most likely).