TABLE 3.
Longitudinal clinical characteristics of follow-up Australian sALS cohort (SALSA) (n = 67).
| Clinical characteristics | Mean (SD) or n (%) | ||||||||
| Baseline (n = 67) | Visit 2 (n = 67) | Visit 3 (n = 51) | Visit 4 (n = 34) | Visit 5 (n = 24) | Visit 6 (n = 12) | Visit 7 (n = 3) | Visit 8 (n = 1) | ||
| Age at symptom onset (years) | 61.92 (11.46) | – | – | – | – | – | – | – | |
| Follow-up interval (mths) | – | 6.34 (9.26) | 11.39 (7.71) | 15.45 (9.34) | 19.97 (11.36) | 24.21 (16.06) | 60.94 (3.76) | 25.9 (–) | |
| Age at assessment (years) | 65.31 (11.77) | 65.83 (11.70) | 64.85 (11.5) | 64.75 (10.99) | 63.20 (10.56) | 64.70 (9.65) | 60.94 (3.76) | 59.31 (–) | |
| Disease duration (years) | 1.81 (2.42) | 2.27 (2.48) | 2.76 (2.64) | 3.24 (2.74) | 3.25 (2.31) | 3.97 (2.89) | 4.90 (1.51) | 5.37 (–) | |
| Sex | Male | 38 (56.7%) | 38 (56.7%) | 31 (60.8%) | 18 (52.9%) | 15 (62.5%) | 8 (66.7%) | 3 (100%) | 1 (100%) |
| Female | 29 (43.3%) | 29 (43.3%) | 20 (39.2%) | 16 (47.1%) | 9 (37.5%) | 4 (33.3%) | – | – | |
| Onset type | Spinal | 49 (73.1%) | 49 (73.1%) | 36 (70.6%) | 28 (82.4%) | 20 (83.3%) | 12 (100%) | 3 (100%) | 1 (100%) |
| Bulbar | 18 (26.9%) | 18 (26.9%) | 15 (29.4%) | 6 (17.6%) | 2 (16.7%) | – | – | – | |
| ALSFRS | 35.64 (8.4) | 32.39 (8.38) | 30.18 (8.19) | 27.44 (9.98) | 25.33 (9.02) | 22.75 (9.90) | 18.67 (6.66) | 24 (–) | |
Displayed as numbers of participants, means, and standard deviations. ALSFRS, amyotrophic lateral sclerosis functional rating scale.