Table 3. Logistic regression factors of perioperative HI.
| Parameter | Univariate | Multivariate | |||||
|---|---|---|---|---|---|---|---|
| OR | 95% CI | P value | OR | 95% CI | P value | ||
| Sex (female vs. male) | 1.00 | 0.44–2.25 | 0.9965 | ||||
| Age (years) | 1.02 | 0.99–1.04 | 0.1687 | ||||
| BMI (kg/m2) | 1.00 | 0.93–1.08 | 0.9678 | ||||
| Previous abdominal surgery (yes vs. no) | 1.09 | 0.47–2.51 | 0.8432 | ||||
| ASA (III–IV vs. I–II) | 1.19 | 0.53–2.69 | 0.6747 | ||||
| Diabetes (yes vs. no) | 3.65 | 1.52–8.76 | 0.0037 | 2.79 | 1.10–7.10 | 0.031 | |
| Cardiovascular disease (yes vs. no) | 1.31 | 0.52–3.27 | 0.5695 | ||||
| Renal diseases (yes vs. no) | 2.81 | 0.49–16.16 | 0.2468 | ||||
| Liver diseases (yes vs. no) | 1.33 | 0.18–9.89 | 0.7784 | ||||
| Pulmonary disease (yes vs. no) | 0.50 | 0.09–2.73 | 0.4257 | ||||
| Cerebrovascular diseases (yes vs. no) | 2.05 | 0.33–12.89 | 0.4430 | ||||
| Tumour site (right vs. left) | 0.74 | 0.32–1.68 | 0.4667 | ||||
| Size of the adrenal tumour | 1.48 | 1.14–1.92 | 0.003 | 1.43 | 1.09–1.86 | 0.009 | |
| PASS score | 1.05 | 0.85–1.30 | 0.6510 | ||||
| Genetic syndrome (yes vs. no) | 0.30 | 0.06–1.47 | 0.1364 | ||||
| Surgeon (others vs. the most experienced) | 1.82 | 0.80–4.14 | 0.1536 | ||||
| Blood transfusion | 3.79 | 0.72–20 | 0.116 | ||||
| Preoperative alpha-blockade (selective vs. nonselective) | 1.04 | 0.44–2.45 | 0.9338 | ||||
| Preoperative beta-blockade (yes vs. no) | 1.38 | 0.6–3.17 | 0.448 | ||||
| Urine metanephrine level >10 ULN (µg/24 h) | 2.02 | 0.6–6.83 | 0.256 | ||||
| Urine normetanephrine level >10 ULN (µg/24 h) | 1.46 | 0.48–4.41 | 0.508 | ||||
| Urine methoxytyramine level >10 ULN* (µg/24 h) | 1.21 | 0.07–20.67 | 0.895 | ||||
*, absolute values of methoxycatecholamines were not significant risk factors HI: urine metanephrine (OR 1.17, 95% CI: 0.92–1.47, P=0.197), urine normetanephrine (OR 1.09, 95% CI: 0.98–1.22, P=0.13) and urine methoxytyramine (OR 1.18, 95% CI: 0.45–3.11, P=0.738). HI, hemodynamic instability; OR, odds ratio; CI, confidence interval; BMI, body mass index; ASA, American Society of Anaesthesiologists physical status classification system; PASS, Pheochromocytoma of the Adrenal Gland Scaled Score; ULN, upper limit of normal.