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. 2021 Jan 30;30(1):87–102. doi: 10.1093/hmg/ddaa284

Figure 4.

Figure 4

The BBSome subcomplex (BBSome1·5·8·9) consisting of BBS1, BBS5, BBS8 and BBS9 is found in photoreceptor cilia in the absence of BBS7 in Bbs7−/− retinal photoreceptors. (a) Sucrose gradient fractionation shows that the peak fractions of BBS1, BBS5, BBS8 and BBS9 are shifted from fraction 12 to fraction 10–11 in retinas of Bbs7−/− mice. (b) BBS8, a member of this BBSome1·5·8·9 subcomplex, localizes to photoreceptor ciliary axoneme in Bbs7−/− mice (arrow). (c) BBS9, a member of this BBSome1·5·8·9 subcomplex, is also observed in photoreceptor ciliary axoneme in Bbs7−/− mice (arrow).