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. 2021 Mar 26;12:655528. doi: 10.3389/fimmu.2021.655528

Table 1.

Current clinical trials based on Interferons for COVID-19.

IFN type/Class Subtype Code Delivery route Status Primary purpose
IFN alpha/I 1b NCT04320238 nasal drops Recruiting prevention
NCT04293887 nebulization Not yet recruiting therapeutic
2b NCT04273763 intranasal spray Active, not recruiting therapeutic
NCT04349410 nebulization Completed therapeutic
RPCEC00000308-Sp nasal drops Completed prevention
RPCEC00000337-En nasal drops Completed prevention
RPCEC00000318-Sp systemic Completed therapeutic
NCT04480138 systemic (pegylated) Recruiting therapeutic
NCT04254874 atomization(pegylated) Recruiting therapeutic
NCT04379518 systemic Recruiting therapeutic
(cancer patients)
2b+IFN gamma RPCEC00000307-En systemic Completed therapeutic
us NCT04664010 systemic Active, not recruiting therapeutic
NCT04275388 nebulization Not yet recruiting therapeutic
NCT04534725 intranasal spray Recruiting therapeutic
NCT04251871 aerosol inhalation Recruiting therapeutic
IFN beta/I 1a NCT04647669 systemic Not yet recruiting therapeutic
NCT04315948 systemic Active, not recruiting therapeutic
NCT04492475 systemic Completed therapeutic
NCT04350671 systemic Enrolling by invitation therapeutic
NCT04521400 systemic Not yet recruiting therapeutic
NCT04460547 systemic Not yet recruiting therapeutic
NCT04449380 systemic Recruiting therapeutic
NCT04330690 systemic Recruiting therapeutic
NCT04552379 systemic (pegylated) Recruiting therapeutic
NCT04732949 nebulization Recruiting therapeutic
NCT04350684 systemic Enrolling by invitation therapeutic
NCT04385095 nebulization Recruiting therapeutic
1b NCT04350281 systemic Completed therapeutic
NCT04276688 systemic Completed therapeutic
NCT04465695 systemic Recruiting therapeutic
NCT04647695 systemic Recruiting therapeutic
NCT04494399 systemic Recruiting therapeutic
NCT04611243 systemic Recruiting therapeutic
NCT04356495 nebulization Recruiting therapeutic
NCT04469491 nebulization Suspended therapeutic
1a and 1b NCT04343768 systemic Complete therapeutic
us NCT04324463 systemic Recruiting therapeutic
IFN lambda/III 1a
NCT04344600
systemic (pegylated)) Recruiting prevention and therapeutic
NCT04388709 systemic (pegylated) Withdrawn therapeutic
NCT04354259 systemic (pegylated) Recruiting therapeutic
us NCT04343976 systemic (pegylated) Enrolling by invitation therapeutic
NCT04534673 systemic (pegylated) Recruiting therapeutic

us, not specified.