Table 1. Comparison of patient clinicopathological characteristics between the PIK3CA mutation and PIK3CA wild-type groups.
Characteristic | PIK3CA mutation status (%) | P | |
---|---|---|---|
Mutation (N=11) | Wild-type (N=39) | ||
Age | 52.73±14.157 | 53.72±11.546 | 0.388 |
Tumor size (cm) | 0.096 | ||
≤2 | 6 (54.5) | 18 (46.2) | |
2–5 | 3 (27.3) | 20 (51.2) | |
>5 | 2 (18.2) | 1 (2.6) | |
Tumor location | 0.468 | ||
Left | 7 (63.6) | 20 (51.2) | |
Right | 4 (36.4) | 19 (48.8) | |
No. of positive axillary nodes | 0.712 | ||
0 | 7 (63.6) | 27 (69.2) | |
≤4 | 1 (9.1) | 6 (15.4) | |
4–9 | 2 (18.2) | 5 (12.8) | |
>10 | 1 (9.1) | 1 (2.6) | |
Histological grade | 0.594 | ||
SBR II | 3 (27.3) | 14 (35.9) | |
SBR III | 8 (72.7) | 25 (64.1) | |
TNM stage | 0.447 | ||
I | 6 (54.5) | 13 (33.3) | |
II | 2 (18.2) | 17 (43.6) | |
III | 2 (18.2) | 5 (12.8) | |
IV | 1 (9.1) | 4 (10.3) | |
Relapse | 0.880 | ||
No | 10 (90.9) | 36 (92.3) | |
Yes | 1 (9.1) | 3 (7.7) | |
Metastasis | 0.909 | ||
No | 10 (90.9) | 35 (89.7) | |
Yes | 1 (9.1) | 4 (10.3) | |
Survival status | 0.880 | ||
Live | 10 (90.9) | 36 (92.3) | |
Dead | 1 (9.1) | 3 (7.7) | |
Family cancer history | 0.412 | ||
Yes | 9 (81.8) | 27 (69.2) | |
No | 2 (18.2) | 12 (30.8) | |
P53 status | 0.248 | ||
Negative | 3 (27.3) | 5 (12.8) | |
Positive | 8 (72.7) | 34 (81.2) | |
Ki67 | 0.329 | ||
≤14% | 1 (9.1) | 1 (2.6) | |
>14% | 10 (90.9) | 38 (97.4) |