Figure 1. The Dark⁸², Hpo^N.1.2 mosaic eye results in dramatic tissue overgrowth and pupal lethality.

A.) Lateral view of FRT42D, Dark⁸² mosaic control eye and B.) FRT42D, Dark⁸²,Hpo^N.1.2 mosaic mutant pupal eyes at the same magnification (40x). In both genotypes, mutant tissue displays red pigmentation (w^+mC). Arrows on A and B point to antennae, eyes are oriented with anterior to the left and dorsal to the top. C.) Genomic region of chromosome 2R in which mutant N.1.2 failed to complement (2R:19,462,450..19,506,861). The N.1.2 mutation mapped to the hpo gene locus found in this region (yellow highlight). Image adapted from flybase.org (Gramates 2017).