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. Author manuscript; available in PMC: 2021 Apr 9.
Published in final edited form as: J Allergy Clin Immunol. 2016 Aug 20;139(1):152–165. doi: 10.1016/j.jaci.2016.07.019

Figure 4.

Figure 4.

Unsupervised hierarchical clustering of mRNA expression in AD, psoriasis, ichthyosis, and controls (A) as a heatmap with fold changes/FCHs between diseases and healthy skin. Green box: Cluster of upregulated IL-17-related genes in ichthyosis and psoriasis. +p<0.1, *p<0.05, **p<0.01. red, up-regulation; blue, down-regulation. (B) Unsupervised clustering of samples (phylogenetic tree) based on expression profiles of 45 immune/barrier markers; Distance: Pearson correlation, agglomeration: average.