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. 2021 Mar 19;13(7):485–498. doi: 10.2217/epi-2020-0384

Table 2. . The significant KEGG enrichment pathways analysis with gometh function in R.

Pathway Gene count p-value§ FDR p-value§ p-value FDR p-value
Metabolic pathways 1470 5.12 × 10-18 1.72 × 10-15 9.61 × 10-6 0.003
Endocytosis 246 4.03 × 10-5 7.55 × 10-4 8.67 × 10-5 0.015
Fatty acid metabolism 56 0.011 0.034 3.37 × 10-4 0.028
Apelin signaling pathway 137 0.003 0.015 4.35 × 10-4 0.029
Axon guidance 180 1.94 × 10-4 0.002 8.65 × 10-4 0.042
Synaptic vesicle cycle 78 1.07 × 10-4 0.001 8.54 × 10-4 0.042
Platelet activation 124 0.001 0.009 - -
C-type lectin receptor signaling pathway 104 0.005 0.020 - -
Fc gamma R-mediated phagocytosis 92 0.005 0.021 - -
B cell receptor signaling pathway 80 0.013 0.037 - -

Pathways in both paired t-test and Pearson’s correlation.

Immunity related pathways based on paired t-test only.

§

p-value for paired t-test based pathway.

p-value for Pearson's correlation based pathway.

FDR: False discovery rate.