Table 2. . The significant KEGG enrichment pathways analysis with gometh function in R.
Pathway | Gene count | p-value§ | FDR p-value§ | p-value¶ | FDR p-value¶ |
---|---|---|---|---|---|
Metabolic pathways† | 1470 | 5.12 × 10-18 | 1.72 × 10-15 | 9.61 × 10-6 | 0.003 |
Endocytosis† | 246 | 4.03 × 10-5 | 7.55 × 10-4 | 8.67 × 10-5 | 0.015 |
Fatty acid metabolism† | 56 | 0.011 | 0.034 | 3.37 × 10-4 | 0.028 |
Apelin signaling pathway† | 137 | 0.003 | 0.015 | 4.35 × 10-4 | 0.029 |
Axon guidance† | 180 | 1.94 × 10-4 | 0.002 | 8.65 × 10-4 | 0.042 |
Synaptic vesicle cycle† | 78 | 1.07 × 10-4 | 0.001 | 8.54 × 10-4 | 0.042 |
Platelet activation‡ | 124 | 0.001 | 0.009 | - | - |
C-type lectin receptor signaling pathway‡ | 104 | 0.005 | 0.020 | - | - |
Fc gamma R-mediated phagocytosis‡ | 92 | 0.005 | 0.021 | - | - |
B cell receptor signaling pathway‡ | 80 | 0.013 | 0.037 | - | - |
Pathways in both paired t-test and Pearson’s correlation.
Immunity related pathways based on paired t-test only.
p-value for paired t-test based pathway.
p-value for Pearson's correlation based pathway.
FDR: False discovery rate.